Biomarker Analysis Services

Biomarkers can provide information on the different physiological pathways involved in disease progression and hence can be used to measure the safety and efficacy of the drug for a specific disease indication. Often, biomarkers are primary or secondary endpoints in clinical trials.

The bioanalytical laboratory at Pacific BioLabs can develop and validate methods to analyze biomarkers in preclinical and clinical samples such as plasma, serum, urine, tissue, and CSF. Over the past 20 years, we have performed bioanalytical method development for different biomarkers such as proteins, peptides and carbohydrates using LC/MS/MS, ELISA and activity assays.

To support a preclinical work, PBL has a 14,000 square foot vivarium and we can dose the animals, collect the samples and analyze the samples all within the same facility. The PBL analytical and bioanalytical team also has experience supporting clinical trials and we would be happy to discuss how we can use our experience to support your studies.

Biomarker Analytical Techniques Available

  • Method Development and Validation
  • Analysis to Support Preclinical and Clinical Development
  • ELISA and Activity Assays
  • LC/MS/MS
  • Instrumentation Details

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