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Small Molecule Bioanalysis

Small molecule bioanalysis can be defined as the chemical analysis of compounds within a biological matrix.  Small molecules are traditional pharmaceutical, typically they have a low molecular weight of less than 900 Daltons and regulate a biological process.  As a drug moves through the drug development process, a variety of preclinical and clinical studies take place in which the drug would need to be analyzed within a biological matrix, usually serum or plasma.  Common small molecule bioanalytical studies are: pharmacokinetic (PK) studies, pharmacodynamics (PD) studies and biomarker assays.  To learn more about these types of studies, please see the following pages:

PK Bioanalysis

In Vivo PK, PD and TK Studies

Biomarker Analysis

 

 

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